pisshole UK /ˈpɪs.həʊl/US /ˈpɪs.hoʊl/ noun2 •(slang, vulgar) The urinary meatus, the external orifice of the urethra.As is, he and I know the wetness is natural lubricant oozing from the pisshole of his big dick. — 2009 •(slang, vulgar) An unpleasant place.High school crowds; doinks with nothing better to do than come down to this pisshole and wave through the glass partition at the biggest jerk in the whole gang. — 1989 formspissholes