pick-me noun2 •(slang, offensive) A person who acts against the interests of their own (typically marginalized) group in the hope of obtaining majority favour.Pick-mes are ideal for the role of the token minority friend since they often fall in line with racist beliefs used against their own community. — 2020 •(slang, offensive) Synonym of pick-me girl.Yet the “pick me” culture, a phenomenon where some women announce their willingness to adhere to these arbitrary standards, is evident on Twitter and other social media sites. — 2020 formspick mes · pick-mes