PFAS /ˈpiːfæs/ noun4 •a perfluoroalkyl substance •a polyfluoroalkyl substance •Acronym of perfluoroalkyl or polyfluoroalkyl substance (“a type of environmental pollutant”).The US company 3M was the first to manufacture a PFAS commercially – the C8, PFOA. — 2019 •Initialism of pollen-food allergy syndrome. formsPFASs