pestiferous

adjective2

1. •
   Containing organisms that cause contagious diseases.

   • because he hath vouchsafed to preserue our nation from such fountains, from serpents and venemous wormes, & from al other pestiferous & contagious creatures. — 1589
2. •
   Annoying, vexatious.

   • No, prelate; such is thy audacious wickedness, / Thy lewd, pestiferous, and dissentious pranks, / As very infants prattle of thy pride. — 1591