perfidious UK /pəˈfɪdi.əs/US /pɚˈfɪdi.əs/ adjective1 •Of, pertaining to, or representing perfidy; disloyal to what should command one's fidelity or allegiance.TRINCULO (speaking about Caliban): By this light, a most perfidious and drunken / monster: when his god's asleep, he'll rob his bottle. — 1610 formsmore perfidious · most perfidious