Panamanian /pænəˈmeɪni.ən/noun 2adjective 1forms 1 noun2 •A person from Panama or of Panamanian descent.Most Panamanians are adamant that the canal, completed in 1914, will not return to U.S. control. — 2025 •A person from Panama City. adjective1 •Of, from, or pertaining to Panama or Panamanian people.Now when Ruthie says come see her / In her honky-tonk lagoon / Where I can watch her waltz for free / 'Neath her Panamanian moon — 1966 formsPanamanians