pachydermy noun2 •A condition in which the skin thickens and becomes hardened or verrucous.If, as the inflammation recurs, the pachydermy spread beyond the point originally attacked, all the different grades of the disease are often exhibited simultaneously in the same extremity. — 1883 •Insensitivity.The haughty foreign secretary, to whom for the next fifty years all stories of aristocratic pachydermy were attached, was still to come. — 1972