pachydermatous adjective3 •Of or relating to the pachyderms. •(literary, humorous) Thick-skinned; insensitive.The impressionable peasant leads a larger, fuller, more dramatic life than the pachydermatous king. — 1891 •Like an elephant.The sanda comes up tail foremost, and blocks the orifice with his pachydermatous appendage. — 1913 formsmore pachydermatous · most pachydermatous