nucleus UK /ˈnjuː.kli.əs/US /ˈnuː.kli.əs/ noun7 •The core, central part of something, around which other elements are assembled. •The massive, positively charged central part of an atom, made up of protons and neutrons. •A large membrane-enclosed organelle found in eukaryotic cells which contains genetic material. •The central part of a syllable, most commonly a vowel. •An initial part or version that will receive additions.This collection will form the nucleus of a new library. •A small bee-hive used to create a colony from a larger existing one. •A ganglion, cluster of many neuronal bodies where synapsing occurs. formsnuclei · nucleuses