nodopathy noun1 •Any peripheral neuropathy caused by changes restricted to the nodes of Ranvier and paranodal regions.Acute motor axonal neuropathy (AMAN), the axonal motor variant of GBS, is the prototypic nodopathy; antibodies against GM1 ganglioside—an axolemmal nodal antigen—lead to disruption of sodium channels. — 2020 formsnodopathies