neutralize UK /ˈnjuːtɹəlaɪz/US /ˈnutɹəˌlaɪz/ verb4 •To make (something) even, inactive or ineffective.The antidote neutralized the toxin. •To make (an acidic or alkaline substance) chemically neutral. •(euphemistic) To kill.At the beginning of the opening game, Shepard becomes the first human Spectre, an elite operative given broad authority to neutralize threats to galactic order in the galaxy. — 2019 •To make (a territory, etc.) politically neutral.All the powers involved are committed not only to stay out of a given territory, but also to reenter it if any one of them violates the independence of the neutralized country. — 1965 formsneutralized · neutralizing · neutralizes