neuroleptic adjective 1noun 1forms 3 adjective1 •Having antipsychotic properties.By mouth in doses of 2 to 3 grains, combined with neuroleptic drugs, it has enabled us to bring about a certain number of improvements in chronic schizophrenics. — 1959 noun1 •An antipsychotic drug.Thus initially neuroleptics may increase DA turnover and possibly even its action depending on the degree of postsynaptic block. — 2001 formsneuroleptics · more neuroleptic · most neuroleptic