mouthwise adjective 1adverb 1 adjective1 •By, or in terms of, the mouth or mouth-like part.We can't get Mr. Wideman to eat. […] Explains the options, mouthwise or IVs, folks, and how the mouthwise method is much preferred by doctors, staff, studies, you know. — 2022 adverb1 •By, or in terms of, the mouth or mouth-like part.A kind of mouse-trap […] woven with string instead of bamboo: it is fastened to a tree mouthwise by a string; the animal comes rushing in and pulls the weaving tight and tighter around itself: […] — 1892