monotopic

adjective3

1. •
   that interact with only one leaflet of the lipid bilayer

   • The fracture faces were free of particles, indicating that PDS-His 6 does not dip deeply into membranes, probably representing a monotopic membrane protein. — 2015
2. •
   Relating to monotopism
3. •
   That has only one site at which another compound can form a complex