mofo UK /ˈməʊfəʊ/US /ˈmoʊfoʊ/adjective 1adverb 1noun 1forms 1 adjective1 •(slang, vulgar) Syllabic abbreviation of motherfucking.Man, he's got a big mofo truck. adverb1 •(slang, vulgar) Syllabic abbreviation of motherfucking. noun1 •(slang, vulgar) Syllabic abbreviation of motherfucker.Man, he's a big mofo. formsmofos
