mistrustful adjective4 •Having mistrust, lacking trust (in someone or something).[…] I hold it cowardice To rest mistrustful where a noble heart Hath pawn’d an open hand in sign of love — 1591 •Expressing or showing a lack of trust.He lookt askew with his mistrustfull eyes, And nycely trode, as thornes lay in his way — 1590 •Having a suspicion, imagining or supposing (that something undesirable is the case).The mender of roads was now coming to himself, and was mistrustful of having made a mistake in his late demonstrations; but no. — 1859 •(no longer used) Causing mistrust, suspicions, or forebodings.Vp we gad, owt spredding oure sayls and make to the seaward: Al creeks mistrustful with Greekish countrye refusing. — 1582 formsmore mistrustful · most mistrustful