misfold /ˈmɪsfoʊld/noun 1/mɪsˈfoʊld/ verb 1forms 3 noun1 •An incorrect or abnormal folding. misfold /mɪsˈfoʊld/ verb1 •To fold into an unusual or incorrect tertiary structure; misfolded proteins occur in various diseases, including amyloidoses and dementias, although the question of causation versus consequence is not yet definitively answered for dementias.The prionopathies are best known among the neurodegenerative diseases for their ability to misfold, self-propagate, and infect other organisms. — 2021 formsmisfolded · misfolding · misfolds