metabolize /mɪˈtæbəˌlaɪz/ verb4 •To undergo metabolism. •To cause a substance to undergo metabolism.Among the many types of juice, grapefruit stands out from the pack because it changes the way some people absorb and metabolize different drugs. — 2004 •To absorb and process as if by metabolism. •To produce a substance using metabolism. formsmetabolized · metabolizing · metabolizes