melarsoprol UK /mɛˈlaː.sə(ʊ).pɹɒl/US /məˈlɑɹ.səˌpɹɔl/ noun1 •An organic arsenic compound, C₁₂H₁₅AsN₆OS₂, administered intravenously to treat late-stage African trypanosomiasis (sleeping sickness).They still use the drug melarsoprol, which, Dr. Pécoul said, “is not effective and sometimes kills.” — 2008