mandylion UK /mɑnˈdɪlɪən/US /mænˈdɪli.ən/ noun1 •often Mandylion: the Image of Edessa, a holy relic consisting of a piece of cloth upon which an image of the face of Jesus Christ had been miraculously imprinted without human intervention (that is, an acheiropoieton); an artistic depiction of this relic.These legends not only established the value of the Mandylion and the Vera Icon as authentic portraits of Christ, but also as acheiropoieta, i.e., images made without the intervention of human hands. — 1995 formsmandylions