Manchegan adjective 1noun 1forms 3 adjective1 •Of, from or relating to La Mancha. noun1 •A native or inhabitant of the La Mancha region (formerly province) of Spain.Good heavens! where is the man, who can worthily express the rage and indignation which entered into the heart of our Manchegan, when he saw himself handled in this manner? — 1755 formsManchegans · more Manchegan · most Manchegan