lesbro UK /ˈlɛzˌbɹəʊ/US /ˈlɛzˌbɹoʊ/ noun2 •(slang) A male friend or companion of a lesbian.Isaac, a 20-year-old gay male who lives with a lesbian and her bi-sexual girlfriend, did not realize he was a "lesbro" until he moved in with these two women. — 2008 •(slang, offensive) A man who is sycophantic or groveling to lesbians and/or bisexual women. formslesbros