leprosy /ˈlɛpɹəsi/ noun7 •An infectious disease caused by the bacterium Mycobacterium leprae, gradually producing nerve damage and patches of skin necrosis and historically handled by permanently quarantining its sufferers.Then is it surely a leprosy — 1535 •A contagious disease causing similar effects in animals. •(nonstandard, old-fashioned) Similar contagious skin diseases causing light patches of scaly skin, particularly psoriasis, syphilis, vitiligo, scabies, and (biblical) the various diseases considered "tzaraath" in the Old Testament. •Ellipsis of murine leprosy or feline leprosy (“diseases caused in rodents and cats by Mycobacterium lepraemurium”). •(figurative) Anything considered similarly permanent, harmful, and communicable, particularly when such a thing should be handled by avoidance or isolation of its victims.Sin is a spiritual leprosy. •(no longer used) Synonym of mange and glanders in horses. •(no longer used, rare) Synonym of leprosarium: a place for the housing of lepers in isolation from the rest of society. formsleprosies