labile /ˈleɪ.baɪl/ adjective4 •Apt or likely to change.Pythagoras [said] that each thing or matter was ever gliding and labile. — 1603 •Of a compound or bond, kinetically unstable; rapidly cleaved (and possibly reformed).Certain drugs can be conjugated to polymer molecules with a linkage that is labile at low pH to effect controlled release in a cellular endosome.Water ligands typically bind metals in a labile fashion and are rapidly interchanged in aqueous solution. •Of a verb, able to change valency without changing its form; especially, able to be used both transitively and intransitively without changing its form. •Liable to slip, err, fall, or apostatize. formsmore labile · most labile