jake leg noun1 •(US, slang) Paralysis of the feet and ankles caused by the consumption of TOCP (tri-ortho-cresyl phosphate) or methyl alcohol, found in adulterated moonshine or Jamaica ginger extract.Out-of-town patients came in droves for the treatment of [jake leg]. Jake leg was caused by drinking methyl (wood) alcohol rather than ethyl alcohol. There's a world of difference. — 2010