irreversible UK /ˌɪr.ɪˈvɜː.sə.bəl/US /ˌɪr.ɪˈvɝ.sə.bəl/ adjective3 •Incapable of being reversed or turned about or back; incapable of being made to run backwards. •Incapable of being reversed to the original state without consumption of free energy and increase of entropy. •Incapable of being reversed, recalled, repealed, or annulled.“Even under a variety of policies, including plastic product reduction, waste management, and environmental recycling, microplastic pollution is irreversible and escalating.” — 2024