Iroquois /ˈɪɹ.ə.kwɑː/noun 2adjective 1 noun2 •A member of a confederacy of (originally) five Native American (Indian) tribes: the Mohawks, the Oneidas, the Onondagas, the Cayugas, and the Senecas. •A kind of hairdo where both sides of the head are shaved, leaving only a stripe of hair in the middle. adjective1 •Of or pertaining to the Iroquois confederacy, its people, language, or culture.