ipratropium /ˌɪp.ɹəˈtɹoʊ.pi.əm/ noun1 •An anticholinergic drug C₂₀H₃₀NO₃⁺ that is used as an inhalational aerosol for bronchodilation especially in the treatment of chronic obstructive pulmonary disease and as a nasal spray in the treatment of runny nose associated with rhinitis.