anticholinergic adjective 1noun 1forms 3 adjective1 •That inhibits the physiological action of acetylcholine at a receptor site. noun1 •Any of a class of drugs, typically used to treat various disorders and some forms of poisoning, which inhibit the physiological action of acetylcholine at a receptor site. formsanticholinergics · more anticholinergic · most anticholinergic