interstate /ˈɪntɚˌsteɪt/adjective 1adverb 1noun 1forms 1 adjective1 •(US, Australia) Of, or relating to two or more states.Jordan Gee, 37, of Nanticoke, Pennsylvania, was charged with three felony counts of threats against the president and one count of interstate threats, according to the Justice Department. — 2024 adverb1 •(US, Australia) Crossing states (usually provincial state, but also e.g. multinational sense).The truck driver drove interstate to unload. noun1 •(US) A freeway that is part of the Interstate Highway System.The speed-limit increase would not apply to Delaware, where the interstates are all near populated areas. — 1987 formsinterstates