indefatigable UK /ˌɪn.dɪˈfæt.ɪ.ɡə.bəl/US /ˌɪn.dəˈfæt.ɪ.ɡə.bəl/ adjective1 •Extremely persistent and untiring.[...] But he was at the same Time an excellent Scholar, and most indefatigable in teaching the two Lads. — 1749 formsmore indefatigable · most indefatigable