hypotonic UK /hʌɪpə(ʊ)ˈtɒnɪk/US /haɪpəˈtɑnɪk/ adjective2 •Having a lower osmotic pressure than another. •Showing less than normal tension in the muscles or muscle tissue.But always he went the full length, crying until he was completely exhausted, worn out, hypotonic. — 1983 formsmore hypotonic · most hypotonic