hypospadias UK /ˌhʌɪ.pəʊˈspeɪ.di.əs/US /ˌhaɪ.pəˈspeɪ.di.əs/ noun1 •A congenital condition in males in which the opening of the urethra is on the underside of the penis.At the same time, they corrected Jack’s hypospadias, a condition that meant his urethra opened at the base of his penis, moving it further up so he could pee more like a boy. — 2016 formshypospadiases