hypercolonize /ˌhaɪ.pɚˈkɑl.ə.naɪz/ verb1 •To colonize excessively.In addition to a dsdA mutant, dsdC mutants hypercolonize relative to wild type, suggesting that there are mechanisms of D-serine dependent virulence gene expression that are independent of DsdC [31 ]. — 2015 formshypercolonized · hypercolonizing · hypercolonizes