Hotan /ˈhoʊ.tɑn/ noun2 •A county-level city of Hotan prefecture, Xinjiang autonomous region, China.Two Chinese men view an exhibit on the East Turkestan Islamic Movement, Hotan, Xinjiang Uighur Autonomous Region, 2003. — 2006 •a city and prefecture in Xinjiang, in the far west of China, on the southern edge of the Taklamakan Desert