homeboy /ˈhoʊm.bɔɪ/noun 3pronoun 1forms 1 noun3 •(informal) Someone, particularly a male acquaintance, from one’s hometown.When the boy next door; Don't want to be my homeboy no more; Saw something that I never saw before; I think he wants to be my baby — 2004 •(informal) A close friend or fellow member of a youth gang. •(informal) A person. pronoun1 •(slang) He or him.Homeboy rafikied a peacock with a squeegee. — 2023 formshomeboys