HIV /ˌeɪtʃˌaɪˈviː/ noun5 •The infection caused by HIV. •Initialism of human immunodeficiency virus.There have been other drugs since reticulose that I became aware of the successes of, some even able to claim "cure," even turning people from HIV-positive to negative. — 1998 •Initialism of header isolation valve. •Initialism of hydraulic isolation valve. •Initialism of helium isolation valve.