HBD adjective 1noun 2phrase 1 adjective1 •Having two of the same allele at a locus, or base at an SNP, where both copies are from a single ancestor strand. noun2 •Having two of the same allele at a locus, or base at an SNP, where both copies are from a single ancestor strand. •Initialism of human biodiversity. phrase1 •(Internet) Abbreviation of happy birthday.