half-life /ˈhæfˌlaɪf/ noun4 •The time required for half the nuclei in a sample of an isotope to undergo radioactive decay. •In a chemical reaction, the time required for the concentration of a reactant to fall from a chosen value to half that value. •The time it takes for a substance (drug, radioactive nuclide, or other) to lose half of its pharmacological, physiologic, or radiological activity. •The amount of time it takes for an idea or a fashion to lose half of its influential power.Most books of scholarship have surprisingly short intellectual half-lives during which they make a difference" — 1991 formshalf-lives