frame rail /ˈfreɪmˌreɪl/ noun2 •Each of the two main longitudinal structural members of a body‑on‑frame vehicle, running parallel front to rear and supporting the chassis, to which cross‑members, suspension, drivetrain, and body are attached.It has been proposed that the length of the middle, parallel portion of the sub-frame comes flush with the inner side of the lower flange of the main frame rail. — 1912 •A horizontal structural member of a furniture frame, typically joining the legs or vertical posts, providing support and rigidity; commonly found in tables, chairs, cabinets, and beds.The frame rails must be firmly mortised into the legs to ensure stability. — 1901 formsframe rails