dysphoria /dɪsˈfɔːɹi.ə/ noun2 •A state of feeling unwell or unhappy; a feeling of emotional and mental discomfort and suffering from restlessness, malaise, depression, or anxiety.Chronic dysphoria can be secondary to a debilitating medical illness, a psychiatric disorder, or both (Akiskal, 1983). — 1990 •Ellipsis of gender dysphoria. formsdysphorias