drug-addled adjective1 •mentally mixed-up or confused due to the usage of mind-bending drugs.When HBO airs “Behind the Candelabra” on May 26, the world will get to see Matt Damon play Liberace’s drug-addled, surgically enhanced lover – a role about as far from Jason Bourne as it gets. — 2013 formsmore drug-addled · most drug-addled