downer

noun6

1. •
   (slang) Any drug that has depressant qualities.

   • Eye Girl is very moody. She is always zooted up on some really foul combination of uppers and downers and Rollerblading. Her bouts of Rollerblading seem to coincide with fights with Eye Guy. — 1997
2. •
   (slang) A negative drug trip.

   • Normally those pills give me a boost, but last night they gave me a downer.
3. •
   (slang) Something or someone disagreeable, dispiriting or depressing; a killjoy.

   • You don't really need to know me. I'm kind of a downer. — 2009
4. •
   A livestock animal that has collapsed.

   • The ten-dollar bill was for eating money and the prod pole to be used when the train stopped for water in getting "downers" back on their feet. — 1964
5. •
   A form of industrial action in which workers down tools and refuse to work.

   • In the Workplace Industrial Relations Survey, a strike may be a downer or a stoppage as defined by the Department. — 1978
6. •
   (slang, no longer used) A sixpence.