difficile UK /ˈdɪ.fɪ.saɪl/US /ˈdɪ.fə.səl/ adjective2 •(no longer used) Hard to work with; stubborn. •(no longer used) Difficult.[…] forasmuch as he was to judge of an internall beauty, of a difficile knowledge, and abstruse discovery. — 2006 formsmore difficile · most difficile