destressify verb2 •(informal) To reduce or eliminate emotional stress.I decided in the interest of trying to destressify that I would leave early for the spa so I could have a peaceful ride and not rush. — 2002 •(informal) To reduce or eliminate emotional stress from (someone or something).I know it’s a tough pill to swallow, particularly after being inundated with the demands of a music school, but I hope this helps destressify you by peering at it from several different perspectives. — 2004 formsdestressified · destressifying · destressifies