despite /dɪˈspaɪt/preposition 1noun 3verb 1forms 3 preposition1 •even with something that could have stopped it from happeningDespite being a near-mirror image my of right, my left hand is terrible at these stuff. noun3 •Evil feeling; malice, spite, annoyance.And for these Corcyraeans—neither receive them into alliance in our despite, nor be their abettors in crime. — 1874 •(no longer used) Disdain, contemptuous feelings, hatred.A fals double tunge is more fiers and fell Then Cerberus the cur couching in the kenel of hel; Wherof hereafter, I thinke for to write, — 1515 •(no longer used) Action or behaviour displaying such feelings; an outrage, insult.a despite done against the Most High — 1667 verb1 •(no longer used) To vex; to annoy; to offend contemptuously. formsdespited · despiting · despites