deoxycorticosterone UK /diːˌɒk.sɪˌkɔː.tɪk.əʊˈstɛ.ɹəʊn/US /diˌɑk.sɪˌkɔɹ.tɪˈkɑ.stəˌɹoʊn/ noun1 •A steroid hormone, produced in the adrenal cortex; sometimes manufactured synthetically for use in cases of adrenal insufficiency. formsdeoxycorticosterones