de novo UK /deɪˈnəʊvəʊ/US /deɪˈnoʊvoʊ/adjective 1adverb 1 adjective1 •Anew, afresh, from the beginning; without consideration of previous instances, proceedings or determinations.Such development was not de novo; antecedents are apparent.He filed a motion for a de novo hearing. adverb1 •Anew (from the beginning).Having found the lower court's analysis wrong, the appellate court undertook a review de novo.