cross-dress /ˈkɹɔsˈdɹɛs/ verb2 •To wear clothes typically associated with the opposite sex.The need to cross-dress is no more understood than the natural forms of differing sexual orientation. — 1976 •To display (on the surface of a dendritic cell) antigens produced by a different cell.Such DC are cross-dressed because they are wearing peptide-MHC complexes generated by other cells. — 2006 formscross-dressed · cross-dressing · cross-dresses