colchicine UK /ˈkɒl.tʃɪs.iːn/US /ˈkɑl.t͡ʃəˌsiːn/ noun1 •A highly toxic alkaloid, chemical formula C₂₂H₂₅NO₆, originally extracted from plants of the genus Colchicum and formerly used to treat rheumatic complaints, now used mainly in the treatment of gout.Gloriosa superba: spectacularly beautiful climbing lily. Roots, stalks, leaves contain an acrid narcotic, superbine, as well as colchicine and choline. Three grains of colchicine are fatal. Hawaii. — 1964 formscolchicines